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1

Auf dem Weg zum Verständnis der Immunsuppression

Prof. Dr. Horst Kessler, Dr. Dale F. Mierke, Dr. David Donald, Dr. Mark Furber

Journal:

Angewandte Chemie

Year:

1991

File:

PDF, 289 KB

1991

2

Mechanisms regulating the expression, self-maintenance, and signaling-function of the bradykinin B2 and B1 receptors

Gregory N. Prado, Linda Taylor, Xiaofeng Zhou, Dennis Ricupero, Dale F. Mierke, Peter Polgar

Journal:

Journal of Cellular Physiology

Year:

2002

Language:

english

File:

PDF, 285 KB

english, 2002

3

Threonine6-bradykinin: Conformational study of a flexible peptide in dimethyl sulfoxide by NMR and ensemble calculations

Maria Pellegrini, Marina Gobbo, Raniero Rocchi, Evaristo Peggion, Stefano Mammi, Dale F. Mierke

Journal:

Year:

1996

Language:

english

File:

PDF, 905 KB

english, 1996

4

Conformational characterization of a peptide mimetic of the third cytoplasmic loop of the G-protein coupled parathyroid hormone/parathyroid hormone related protein receptor

Maria Pellegrini, Miriam Royo, Michael Chorev, Dale F. Mierke

Journal:

Year:

1996

Language:

english

File:

PDF, 1.47 MB

english, 1996

5

Vancomycin: Interactions with a model cell membrane

Simona Golič Grdadolnik, Dale F. Mierke

Journal:

Year:

1997

Language:

english

File:

PDF, 162 KB

english, 1997

6

Structure, dynamics, and topological orientation of the polyether, ionophore antibiotic monensin, in a micellar environment

Eduardo Mercurio, Maria Pellegrini, Dale F. Mierke

Journal:

Year:

1997

Language:

english

File:

PDF, 212 KB

english, 1997

7

Structural characterization of peptide hormone/receptor interactions by NMR spectroscopy

Maria Pellegrini, Dale F. Mierke

Journal:

Year:

1999

Language:

english

File:

PDF, 479 KB

english, 1999

8

NMR analysis of peptide structure and bioactivity

Journal:

Year:

1999

Language:

english

File:

PDF, 10 KB

english, 1999

9

Conformational Analysis by NMR and Distance-Geometry Techniques of Deltorphin Analogs

Ettore Benedetti, Carla Isernia, Flavia Nastri, Carlo Pedone, Michele Saviano, Dale F. Mierke, Pietro Melchiorri, Lucia Negri, Rosa Luisa Potenza, Cinzia Severini, Vittorio Erspamer

Journal:

European Journal of Organic Chemistry

Year:

1998

Language:

english

File:

PDF, 353 KB

english, 1998

10

Structural characterization of lipopeptide agonists for the bradykinin B2 receptor

Craig Giragossian, Elena Nardi, Caroline Savery, Maria Pellegrini, Stefania Meini, Carlo A. Maggi, Anna Maria Papini, Dale F. Mierke

Journal:

Year:

2001

Language:

english

File:

PDF, 147 KB

english, 2001

11

Structural Consequences of Metal Complexation of cyclo[Pro-Phe-Phe-Ala-Xaa]2 Decapeptides

Gabriella Saviano, Filomena Rossi, Ettore Benedetti, Carlo Pedone, Dale F. Mierke, Annamaria Maione, Giancarlo Zanotti, Teodorico Tancredi, Michele Saviano

Journal:

Chemistry - A European Journal

Year:

2001

Language:

english

File:

PDF, 177 KB

english, 2001

12

Moleküldynamikrechnungen für Peptide in Dimethylsulfoxid: Eliminierung von Vakuumeffekten

Michael Kurz, Dr. Dale F. Mierke, Prof. Dr. Horst Kessler

Journal:

Angewandte Chemie

Year:

1992

File:

PDF, 263 KB

1992

13

Bestimmung der relativen Konfiguration durch Distanzgeometrie-Rechnungen mit Proton-Proton-Abständen aus NOESY-Spektren

Dr. Michael Reggelin, Dr. Matthias Köck, Dr. Kilian Conde-Frieboes, Dr. Dale F. Mierke

Journal:

Angewandte Chemie

Year:

1994

File:

PDF, 418 KB

1994

14

Skalare Kopplungen – ihre Analyse und ihre Verwendung zur Strukturaufklärung

Dr. Matthias Eberstadt, Dr. Gerd Gemmecker, Prof. Dr. Dale F. Mierke, Prof. Dr. Horst Kessler

Journal:

Angewandte Chemie

Year:

1995

Language:

german

File:

PDF, 2.90 MB

german, 1995

15

Toward the Understanding of Immunosuppression

Prof. Dr. Horst Kessler, Dr. Dale F. Mierke, Dr. David Donald, Dr. Mark Furber

Journal:

Angewandte Chemie International Edition

Year:

1991

Language:

english

File:

PDF, 407 KB

english, 1991

16

Calculation of Molecular Dynamics for Peptides in Dimethyl Sulfoxide: Elimination of Vacuum Effects

Dipl.-Chem. Michael Kurz, Dr. Dale F. Mierke, Prof. Dr. Horst Kessler

Journal:

Angewandte Chemie International Edition

Year:

1992

Language:

english

File:

PDF, 378 KB

english, 1992

17

Determination of the Relative Configuration by Distance Geometry Calculations with Proton–Proton Distances from NOESY Spectra

Dr. Michael Reggelin, Dr. Matthias Köck, Dr. Kilian Conde-Frieboes, Dr. Dale Mierke

Journal:

Angewandte Chemie International Edition

Year:

1994

Language:

english

File:

PDF, 407 KB

english, 1994

18

Scalar Coupling Constants—Their Analysis and Their Application for the Elucidation of Structures

Dr. Matthias Eberstadt, Dr. Gerd Gemmecker, Prof. Dr. Dale F. Mierke, Prof. Dr. Horst Kessler

Journal:

Angewandte Chemie International Edition

Year:

1995

Language:

english

File:

PDF, 3.32 MB

english, 1995

19

Structural insight into the role of the second intracellular loop of the bradykinin 2 receptor in signaling and internalization

Andrea Piserchio, Gregory N. Prado, Ran Zhang, Jun Yu, Linda Taylor, Peter Polgar, Dale F. Mierke

Journal:

Year:

2002

Language:

english

File:

PDF, 250 KB

english, 2002

20

Structural characterization of a cyclic dipeptidomimetic: The effect of ring size on a 1,2,5-trisubstituted-3-oxo-1,4-diazepine system

Andrea Piserchio, Yinglin Han, Michael Chorev, Dale F. Mierke

Journal:

Year:

2002

Language:

english

File:

PDF, 144 KB

english, 2002

21

Homologs of 1,2,5-hexahydro-3-one-1H-1,4-diazepine (DAP) as novel dipeptidomimetics and molecular scaffolds: Efficient preparation of synthons

Yinglin Han, Dale F. Mierke, Michael Chorev

Journal:

Year:

2002

Language:

english

File:

PDF, 228 KB

english, 2002

22

Extracellular domains of the neurokinin-1 receptor: Structural characterization and interactions with substance P

Amy L. Ulfers, Andrea Piserchio, Dale F. Mierke

Journal:

Year:

2002

Language:

english

File:

PDF, 927 KB

english, 2002

23

Bradykinin B2 receptor signaling: Structural and functional characterization of the C-terminus

Andrea Piserchio, Veronica Zelesky, Jun Yu, Linda Taylor, Peter Polgar, Dale F. Mierke

Journal:

Year:

2005

Language:

english

File:

PDF, 241 KB

english, 2005

24

Structural analysis of the human cannabinoid receptor one carboxyl-terminus identifies two amphipathic helices

Kwang H. Ahn, Maria Pellegrini, Natia Tsomaia, Achani K. Yatawara, Debra A. Kendall, Dale F. Mierke

Journal:

Year:

2009

Language:

english

File:

PDF, 346 KB

english, 2009

25

Gas-phase IR spectra of substituted alkylamides

Yalamoori V. Venkatachalapathi, Dale F. Mierke, Joseph P. Taulane, Murray Goodman

Journal:

Year:

1987

Language:

english

File:

PDF, 585 KB

english, 1987

26

Conformational studies of diastereomeric cyclic enkephalins by 1H-NMR and computer simulations

Dale F. Mierke, Pierluigi Lucietto, Murray Goodman, Peter W. Schiller

Journal:

Year:

1987

Language:

english

File:

PDF, 772 KB

english, 1987

27

Enkephalin analogues containing β-naphthylalanine at the fourth position

Dale F. Mierke, Odile E. Said-Nejad, Peter W. Schiller, Murray Goodman

Journal:

Year:

1990

Language:

english

File:

PDF, 1.48 MB

english, 1990

28

A conformational comparision of two stereoisomeric cyclic dermorphin analogues employing nmr and computer simulations

Dale F. Mierke, Peter W. Schiller, Murray Goodman

Journal:

Year:

1990

Language:

english

File:

PDF, 622 KB

english, 1990

29

Combined use of homo- and heteronuclear coupling constants as restraints in molecular dynamics simulations

Dale F. Mierke, Horst Kessler

Journal:

Year:

1992

Language:

english

File:

PDF, 443 KB

english, 1992

30

Improved molecular dynamics simulations for the determination of peptide structures

Dale F. Mierke, Horst Kessler

Journal:

Year:

1993

Language:

english

File:

PDF, 1.33 MB

english, 1993

31

Coupling constants as restraints in ensemble distance driven dynamics

Dale F. Mierke, Ruud M. Scheek, Horst Kessler

Journal:

Year:

1994

Language:

english

File:

PDF, 408 KB

english, 1994

32

Conformation and dynamics of dimeric ureido-balhimycin

Matthias Eberstadt, Wolfgang Guba, Horst Kessler, Herbert Kogler, Dale F. Mierke

Journal:

Year:

1995

Language:

english

File:

PDF, 593 KB

english, 1995

33

Structure of two microcystins: Refinement with nuclear overhauser effects and ensemble calculations

Dale F Mierke, Sabine Rudolph-Böhner, Gerhard Müller, Luis Moroder

Journal:

Year:

1995

Language:

english

File:

PDF, 1.32 MB

english, 1995

34

Conformational Preference and Potential Templates of N-Methylated Cyclic Pentaalanine Peptides

Jayanta Chatterjee, Dale F. Mierke, Horst Kessler

Journal:

Chemistry - A European Journal

Year:

2008

Language:

english

File:

PDF, 698 KB

english, 2008

35

ChemInform Abstract: Parathyroid Hormone and Parathyroid Hormone-Related Protein: Model Systems for the Development of an Osteoporosis Therapy

Dale F. Mierke, Maria Pellegrini

Journal:

Year:

1999

File:

PDF, 25 KB

1999

36

ChemInform Abstract: Peptide Hormone Binding to G-Protein-Coupled Receptors: Structural Characterization via NMR Techniques

Dale F. Mierke, Craig Giragossian

Journal:

Year:

2001

File:

PDF, 25 KB

2001

37

ChemInform Abstract: Structural Consequences of Metal Complexation of cyclo[Pro-Phe-Phe-Ala-Xaa]2 Decapeptides.

Gabriella Saviano, Filomena Rossi, Ettore Benedetti, Carlo Pedone, Dale F. Mierke, Annamaria Maione, Giancarlo Zanotti, Teodorico Tancredi, Michele Saviano

Journal:

Year:

2002

File:

PDF, 27 KB

2002

38

ChemInform Abstract: New Perspective in Peptide Chemistry by N-Alkylation

Horst Kessler, Jayanta Chatterjee, Lucas Doedens, Florian Operrer, Eric Biron, Daniel Hoyer, Herbert Schmid, Chaim Gilon, Victor J. Hruby, Dale F. Mierke

Journal:

Year:

2011

File:

PDF, 18 KB

2011

39

Conformational Analysis of the cis- and trans-Isomers of FK506 by NMR and Molecular Dynamics

Dale F. Mierke, Peter Schmieder, Peter Karuso, Horst Kessler

Journal:

Helvetica Chimica Acta

Year:

1991

Language:

english

File:

PDF, 1.03 MB

english, 1991

40

Peptide Conformation from Coupling Constants: Scalar Couplings as Restraints in MD Simulations

Matthias Eberstadt, Dale F. Mierke, Matthias Köck, Horst Kessler

Journal:

Helvetica Chimica Acta

Year:

1992

Language:

english

File:

PDF, 551 KB

english, 1992

41

Synthesis and Solvent Effects on the Conformation of Hymenistatin 1

Robert K. Konat, Dale F. Mierke, Horst Kessler, Bernhard Kutscher, Michael Bernd, Rainer Voegeli

Journal:

Helvetica Chimica Acta

Year:

1993

Language:

english

File:

PDF, 1.25 MB

english, 1993

42

Global chimeric exchanges within the intracellular face of the bradykinin B2 receptor with corresponding angiotensin II type Ia receptor regions: Generation of fully functional hybrids showing characteristic signaling of the AT1a receptor

Jun Yu, Gregory N. Prado, Linda Taylor, Andrea Piserchio, Abhas Gupta, Dale F. Mierke, Peter Polgar

Journal:

Journal of Cellular Biochemistry

Year:

2002

Language:

english

File:

PDF, 344 KB

english, 2002

43

Role of hydroxyl containing residues in the intracellular region of rat bradykinin B2 receptor in signal transduction, receptor internalization, and resensitization

Gregory N. Prado, Dale F. Mierke, Thomas LeBlanc, Marc Manseau, Linda Taylor, Jun Yu, Ran Zhang, Ruma Pal-Ghosh, Peter Polgar

Journal:

Journal of Cellular Biochemistry

Year:

2001

Language:

english

File:

PDF, 351 KB

english, 2001

44

K317, R319, and E320 within the proximal C-terminus of the bradykinin B2 receptor form a motif important for phospholipase C and phospholipase A2 but not connective tissue growth factor related signaling

Jun Yu, Bin Liu, David Eramian, Dale Mierke, Linda Taylor, Peter Polgar

Journal:

Journal of Cellular Biochemistry

Year:

2004

Language:

english

File:

PDF, 339 KB

english, 2004

45

Activation of ERK, JNK, Akt, and G-protein coupled signaling by hybrid angiotensin II AT1/bradykinin B2 receptors expressed in HEK-293 cells

Jun Yu, David Lubinsky, Natia Tsomaia, Zhenhua Huang, Linda Taylor, Dale Mierke, Javier Navarro, Osman Miraz, Peter Polgar

Journal:

Journal of Cellular Biochemistry

Year:

2007

Language:

english

File:

PDF, 357 KB

english, 2007

46

Peptide hormone binding to G-protein-coupled receptors: Structural characterization via NMR techniques

Dale F. Mierke, Craig Giragossian

Journal:

Medicinal Research Reviews

Year:

2001

Language:

english

File:

PDF, 309 KB

english, 2001

47

Targeting Specific PDZ Domains of PSD-95: Structural Basis for Enhanced Affinity and Enzymatic Stability of a Cyclic Peptide

Andrea Piserchio, Gregory D Salinas, Tao Li, John Marshall, Mark R Spaller, Dale F Mierke

Journal:

Chemistry & Biology

Year:

2004

Language:

english

File:

PDF, 296 KB

english, 2004

48

Characterization of the molecular motions of constitutively active G protein-coupled receptors for parathyroid hormone

Christian Rölz, Dale F. Mierke

Journal:

Biophysical Chemistry

Year:

2001

Language:

english

File:

PDF, 459 KB

english, 2001

49

Molecular characterization of a ligand-tethered parathyroid hormone receptor

Luca Monticelli, Stefano Mammi, Dale F Mierke

Journal:

Biophysical Chemistry

Year:

2002

Language:

english

File:

PDF, 582 KB

english, 2002

50

Coupling constants again: Experimental restraints in structure refinement

Dale F. Mierke, Thomas Huber, Horst Kessler

Journal:

Journal of Computer-Aided Molecular Design

Year:

1994

Language:

english

File:

PDF, 696 KB

english, 1994